Autoimmunity, Inflammation, and Organ Damage
نویسندگان
چکیده
منابع مشابه
Inflammation, immunity, and hypertensive end-organ damage.
For >50 years, it has been recognized that immunity contributes to hypertension. Recent data have defined an important role of T cells and various T cell-derived cytokines in several models of experimental hypertension. These studies have shown that stimuli like angiotensin II, deoxycorticosterone acetate-salt, and excessive catecholamines lead to formation of effector like T cells that infiltr...
متن کاملRheumatological manifestations, organ damage and autoimmunity in hereditary C2 deficiency.
OBJECTIVE To analyse rheumatological manifestations, organ damage and autoimmune responses in a large cohort of patients (n = 45) with homozygous C2 deficiency (C2D) and long-term follow-up. METHODS Medical records were reviewed and were supplemented with a mailed questionnaire for assessment of cardiovascular disease (CVD) risk factors. Organ damage was evaluated using the Systemic Lupus Int...
متن کاملMacrophages and fibroblasts during inflammation, tissue damage and organ injury.
Inflammation is a highly complex cellular surveillance system that is essential for anti-microbial defense and wound healing. The inflammatory process relies on multifaceted coordination among various body systems. Many host cells including leukocytes, fibroblasts, endothelial cells and epithelial cells are involved in the inflammatory process. Cellular receptors, such as Toll-Like-Receptors (T...
متن کاملSOCS, Inflammation, and Autoimmunity
Cytokines play essential roles in innate and adaptive immunity. However, excess cytokines or dysregulation of cytokine signaling will cause a variety of diseases, including allergies, autoimmune diseases, inflammation, and cancer. Most cytokines utilize the so-called Janus kinase-signal transducers and activators of transcription pathway. This pathway is negatively regulated by various mechanis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nihon Naika Gakkai Zasshi
سال: 2013
ISSN: 0021-5384,1883-2083
DOI: 10.2169/naika.102.2529